Catalogue of Molecular Biology Programs Release 6.1 23 Jul 1999 All thanks are in the file biocatal.thanks. ===================================================================== AC BC00104 NAME SAGE DOMAIN Epidemiology DESCRIPTION Statistical Analysis Package for Genetic Epidemiology DESCRIPTION is composed of 18 programs DESCRIPTION AGEON : Estimating the Distribution of Age-of-Onset DESCRIPTION ASSOC : marker-trait Associations in Pedigree Data DESCRIPTION BCROSS : Genetic Hypothesus for Quantitative Data on Inbred DESCRIPTION strains, their F1 and Backcross(es) DESCRIPTION CLUSTR : Power Transformation to Obtain Normality and DESCRIPTION Homoscedasticity from Clustered Data DESCRIPTION FCOR : Family Correlations DESCRIPTION FSP : Family Structure Program DESCRIPTION LODLINK : Lod Score Linkage Analysis DESCRIPTION MAPLOC : Mapping a Disease-Related Trait Relative to a DESCRIPTION Set of Linked markers DESCRIPTION MAXFUN : Function maximization Subroutine DESCRIPTION REGC,REGD,REGTL,REGTN : Segregation Analysis Programs DESCRIPTION RELATE : Relationship to Proband DESCRIPTION SIBPAL : Sib-Pair Linkage Analysis DESCRIPTION DBSORT, RENUM, SPLIT : Toolkit Programs AUTHOR Dr. R.C. Elston RT - ADDRESS Department of Epidemiology and Biostatistics ADDRESS MetroHealth Medical Center ADDRESS 2500 MetroHealth Drive, Room R259 ADDRESS Cleveland, Ohio 44109, USA CONTACT sage@darwin.mhmc.cwru.edu SITE WWW server at URL http://darwin.mhmc.cwru.edu/ SITE-CONTACT webmaster@darwin.mhmc.cwru.edu OS SunOS 4.1.x, Apple Macintosh II, PC 386,486 (MSDOS) LANGUAGE FORTRAN 77 VOLUME - COMMENTS The cost of this package is $500 (US$) AC BC00469 NAME OSA DOMAIN Sequence analysis DOMAIN Protein sequence analysis DOMAIN Epidemiology DOMAIN Phylogeny DOMAIN Statistical significance DOMAIN Comparative analysis DESCRIPTION OSA is a program to find, within an alignment of DESCRIPTION large sequences, those regions with an informative content DESCRIPTION similar to the displayed by the whole alignment and select, DESCRIPTION among them, the shortest empiricaly significant ones. The use of DESCRIPTION these short regions, instead of the larger ones, can save a DESCRIPTION considerable amount of time and resources in molecular screening DESCRIPTION or molecular epidemiology studies. AUTHOR Maria Jesus Martin, Joaquin Dopazo RA Martin M.J., Gonzalez-Candelas F., Sobrino F., Dopazo J.; RT "A method for determining the position and size of optimal RT sequence regions for phylogenetic analysis."; RL J. Mol. Evol. 41:1128-1138(1995). ADDRESS R&D Department, TDI ADDRESS c/ Condes de Torreanaz, 5 ADDRESS 28028, Madrid ADDRESS SPAIN CONTACT martin@tdi.es CONTACT dopazo@tdi.es SITE ftp anonymous ftp.tdi.es SITE Directory /pub/programas/ SITE-CONTACT martin@tdi.es SITE WWW Server at URL http://www.tdi.es/programas/osa-i.htm OS UNIX (Solaris, Irix) LANGUAGE GPC Pascal VOLUME 300K REQUIRES GPC for compiling sources COMMENTS OSA is available as both : executable file for Solaris or COMMENTS Irix operating systems and sources files. GPC compiler is COMMENTS only necessary if you download the sources. .